产品货号：
Z11769
中文名称：
BCL10抗体
英文名称：
Anti-BCL10 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BCL10 Antibody |
| 指标别名 | B cell CLL/lymphoma 10;B cell lymphoma/leukemia 10;BCL10;c E10;CARD like apoptotic protein;CARMEN;cCARMEN;Cellular E10;Cellular homolog of vCARMEN;CIPER;CLAP;hCLAP;mE10 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | BCL10 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Bcl10 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human Bcl10.The immunogen is located within the first 50 amino acids of Bcl-10. |
| 计算分子量 | 26kDa |
| 成分 | Bcl-10 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Bcl-10 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is related to many diseases including cancer.Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include ARC,RAIDD,Apaf-1,caspase-9,and caspase-2.A novel CARD containing protein was recently identified by several groups and designated Bcl10,CIPER,mE10,CARMEN,CLAP.Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene.Overexpression of Bcl10 induces JNK,p38,and NF-百B activation.Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing and induces apoptosis through caspase-9 activation.Bcl10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy.Bcl10 is expressed in many human and murine tissues and cell lines. |
| Uniprot ID | O95999 |
| 基因名全称 | B-cell CLL/lymphoma 10 |
| 蛋白名全称 | B-cell CLL/lymphoma 10 |
| 推荐稀释比 | Bcl-10 antibody can be used for detection of BCL10 by Western blot at 0.5μg/mL.dilution.An approximately 31kDa band can be detected.Antibody can also be used for immunocytochemistry starting at 1μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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